Das Suchergebnis hat sich seit Ihrer Suchanfrage verändert. Eventuell werden Dokumente in anderer Reihenfolge angezeigt.
  • Treffer 4 von 10
Zurück zur Trefferliste

Novel bioreactor internals for the cultivation of spore-forming fungi in pellet form

  • This study introduced an automated long-term fermentation process for fungals grown in pellet form. The goal was to reduce the overgrowth of bioreactor internals and sensors while better rheological properties in the fermentation broth, such as oxygen transfer and mixing time, can be achieved. Because this could not be accomplished with continuous culture and fed-batch fermentation, repeated-batch fermentation was implemented with the help of additional bioreactor internals (“sporulation supports”). This should capture some biomass during fermentation. After harvesting the suspended biomass, intermediate cleaning was performed using a cleaning device. The biomass retained on the sporulation support went through the sporulation phase. The spores were subsequently used as inocula for the next batch. The reason for this approach was that the retained pellets could otherwise cause problems (e.g., overgrowth on sensors) in subsequent batches because the fungus would then show undesirable hyphal growth. Various sporulation supports were tested for sufficient biomass fixation to start the next batch. A reproducible spore concentration within the range of the requirements could be achieved by adjusting the sporulation support (design and construction material), and an intermediate cleaning adapted to this.

Volltext Dateien herunterladen

Metadaten exportieren

Metadaten
Verfasserangaben:Winda Soerjawinata, Isabelle Kockler, Lars Wommer, Robert Frank, Anja Schüffler, Tanja Schirmeister, Roland Ulber, Percy Kampeis
URN:urn:nbn:de:hbz:tr5-1270
DOI:https://doi.org/10.1002/elsc.202100094
Titel des übergeordneten Werkes (Englisch):Engineering in Life Sciences
Verlag:Wiley
Dokumentart:Wissenschaftlicher Artikel (Fachzeitschriften)
Sprache:Englisch
Datum des OPUS-Uploads:07.09.2022
Datum der Erstveröffentlichung:18.05.2022
Veröffentlichende Hochschule:Hochschule Trier
Datum der Freischaltung:07.09.2022
Freies Schlagwort / Tag:bioreactor internals; fungal growth; fungal pellets; repeated-batch fermentation; sporulation conditions
GND-Schlagwort:Bioreaktor; Fermentation; Sporenbildung
Jahrgang:22
Ausgabe / Heft:7
Seitenzahl:10
Erste Seite:474
Letzte Seite:483
Einrichtungen:FB Umweltplanung/-technik (UCB)
DDC-Klassifikation:5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie
6 Technik, Medizin, angewandte Wissenschaften / 66 Chemische Verfahrenstechnik
Lizenz (Deutsch):License LogoCreative Commons - CC BY - Namensnennung 4.0 International